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Printed on acid-free paper Springer is part of Springer Science+Business Media (... we hope to provide the fundamentals of clinical trials design, conduct, analysis, and reporting.... Machin D, Day S, Green S. Textbook of Clinical Trials (2nd edition). West Sussex: Wiley, 2006. 19. Hulley SB, Cummings SR, Browner WS, Grady DG.

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The HIV/AIDS clinical trial experiences beginning more than 3 decades ago offer another lesson on the importance of broader education about the clinical trials process, including DMCs. In the early years of the ACTG/CPCRA trials, many of the interested parties, including sponsors, investigators, investors and the HIV/AIDS community itself.

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